Risk of Myocarditis and other AESI > Risk of COVID Hospitalizations (Part 26)

With a new Cleveland clinic study (n= 53,402) finding that the trivalent 2024-25 flu shot has a -27% VE (27% higher relative risk of infection) for young healthcare workers it warrants comparison with another “vaccine” which also has a modest infection risk reduction at best, in the first few month after administration, but which eventually increases the risk of infection over baseline through RBD specific IgG4 induced immune tolerance to the spike protein which I covered the growing body of evidence for in a previous post.

Compared to the annual flu shot, the COVID modRNA transfections resulted in a 25x higher rate of adverse events over 2.5 years. Among Brighton-case SAEs, the COVID modRNA transfections result in a 1,152x increase in myocarditis, 218x increase in heart attacks, 455x increase in blood clots, 162x increase in fast resting heart rate, 152x increase in shortness of breath, and a 131x increase in hypertension compared to the annual flu shot. VAERS data also suggest a one modRNA transfection related death for every per 33,000 recipients which is much higher than the omicron infection related death rate for non-senior and immunocompetent persons. The uncontrolled synthesis of the antigen (spike protein), random bio-distribution of the polyethylene glycol lipid nano-particles that carry the stabilized modRNA, and the reactogenicity of the polyethylene glycol itself like contributes to these much higher rates of SAEs.

Source: Expanded Spectrum and Increased Incidence of Adverse Events Linked to COVID-19 Genetic Vaccines: New Concepts on Prophylactic Immuno-Gene Therapy, Iatrogenic Orphan Disease, and Platform-Inherent Challenges

Down regulation of ACE2 enzyme

One mechanistic explanation for stress induced cardiomyopathy that results from circulating spike or spike subunit from both the virus and modRNA lipids is the down regulation of the angiotensin 2 converting enzyme which is an essential part of the renin-angiotensin system that maintains cardiovascular homeostasis. The spike protein has been demonstrated to down regulate the angiotensin 2 converting enzyme without the presence of other viral proteins in both in vitro (cell culture) and rodent studies. A 2020 cell culture experiment found that S1 unit expression by itself could inhibit expression of the angiotensin 2 converting enzyme in epithelial lung cells.

Source: Suspected Causes of the Specific Intolerance Profile of Spike -Based Covid-19 Vaccines

High Risk of Coronary Artery Disease

A multivariate meta-analysis of original studies assessing cardiovascular adverse events experienced after the COVID-19 vaxx (n = 15) most of which had a control group (n = 11) found, in their primary analysis that a second dose of the COVID-19 vaxx is associated with an over 3x increase in coronary artery disease compared to unvaxxed control groups and baseline rates within the population.

Healthy Vaccinee Bias created over inflated VE estimates

A common selection bias in observational research known as the healthy volunteer bias or in case of vaccines, the healthy vaccinee bias might have created the initially high VE estimates. The new Cleveland clinic study likely found negative VE for the trivalent flu shot due to an absence of healthy vacinee bias in the employee population.

A nationwide retrospective cohort study conducted in Austria among the entire adult population between January 2021 and December 2023 using national health data from the Austrian epidemiological reporting system found that non-covid mortality was much lower among the vaxxed than unvaxxed population in 2021 regardless of number of doses. This non-covid mortality difference reversed by the second quarter of 2022 for the 1 and 2 dose vaxxed groups compared to unvaxxed and reversed by the fourth quarter of 2022 for booster recipients. As the authors note: ‘the pattern of reduced non-COVID-19 mortality shortly after vaccinations indicates that good health status is associated with vaccination.’ This indicates a healthy recipient bias that eventually waned and reversed in 2022 and 2023.

A systematic review of observational studies (n = 38) and simulation of VE notes that not only do observational studies of VE reviewed routinely miscategorize unverified vaxx status as unvaxxed and apply arbitrary and asymmetrical case counting windows after the vaxx but that using miscategorization and asymmetrical case counting windows you could make an intervention with zero efficacy appear to be 90% effective in the first couple of weeks.

A re-analysis of the Dutch National COVID-19 vaccination and health records dataset (n = 15.9 million) using calculated mortality and VE instead of Cox proportional hazard ratios for matching cohorts between 2021-23 with no 2 week case counting window after vaxx found two large data artifacts: the vaxx appeared to have a 98% VE against all cause mortality within the first four weeks of the first dose and effectiveness against non-covid death was higher than its effectiveness against COVID-19 itself. This suggests a substantial residual healthy vaccinee bias at the start of the observational period that gradually declines over time as the vaxx and unvaxxed mortality rates become more similar and is interpreted as waning VE. The authors note that the most frequent death in the first half of 2021 is cancer. A subgroup analysis of unvaxxed with pre-existing cancer notes that at its peak their mortality rate was 500% higher than their baseline mortality rate.

An evaluation of the Vaccine Effectiveness, Burden and Impact Studies monitoring platform maintained by the European Centre for Disease Prevention and Control for the observation periods of November 2023 to February 2024 (n = 18.7 million) found, using non-COVID19 deaths as a negative control outcome, a 30-65% reduced risk of non-COVID-19 deaths among vaxxed individuals indicating a healthy vaccinee bias unaccounted for in electronic health record based observational research likely due to extremely frail individuals (e.g. patients with terminal illness or going through end of life hospice care) forgoing the vaxx.